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Salivary gland involvement in granulomatosis with polyangiitis: Case report and review of literature

 Department of Clinical Immunology and Rheumatology, King George's Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Kunal Chandwar,
Department of Clinical Immunology and Rheumatology, King George's Medical University, Lucknow - 226 003, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/injr.injr_105_21

We present a case of granulomatosis with polyangiitis (GPA) presenting with salivary gland enlargement and right parotid abscess, left-sided facial palsy, Lacrimal Gland, extraocular muscle involvement and rapidly progressive necrotizing keratitis. Followed by review of available literature on salivary gland involvement in GPA and how salivary gland involvement may be a good prognostic factor with less renal and central nervous system involvement and argue for greater vigilance in diagnosing salivary gland involvement in GPA. An approach to a patient with salivary gland involvement and suspected autoimmune disease wtih Sjögren's Syndrome, IgG4 disease,Antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis and Sarcoidosis is discussed.

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