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 Table of Contents  
BOOK REVIEW
Year : 2022  |  Volume : 17  |  Issue : 1  |  Page : 104-105

Ankylosing spondylitis–Axial spondyloarthritis - 2nd edition


Consultant Rheumatologist, Velammal Speciality Hospital and Research Institute, Madurai; Department of Rheumatology and Medicin, Rosemary Mission Hospital, Tirunelveli, Tamil Nadu, India

Date of Submission01-Nov-2021
Date of Acceptance01-Nov-2021
Date of Web Publication22-Jan-2022

Correspondence Address:
Dr. Subramanian Nallasivan
Velammal Speciality Hospital and Research Institute, Anuppanadi, Madurai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/injr.injr_252_21

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How to cite this article:
Nallasivan S. Ankylosing spondylitis–Axial spondyloarthritis - 2nd edition. Indian J Rheumatol 2022;17:104-5

How to cite this URL:
Nallasivan S. Ankylosing spondylitis–Axial spondyloarthritis - 2nd edition. Indian J Rheumatol [serial online] 2022 [cited 2022 Oct 1];17:104-5. Available from: https://www.indianjrheumatol.com/text.asp?2022/17/1/104/336275





Editors: Muhammad Asim Khan, MD, FRCP, MACP, Nurullah Akkoç, MD

Edition: 2nd Edition

Publisher: Professional Communications Inc., USA

Year: 2021

Pages: 242

ISBN: 978-1-943236-30-5

Authors: Muhammad Asim Khan, Nurullah AkkocThis is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

For reprints contact: [email protected] spondylitis forms part of a spectrum of diseases termed as spondyloarthropathy, and recent evidence in early diagnosis and newer treatment guidelines along with treat to target approach has shown that it is not ankylosing anymore and would rather term it as axial spondyloarthritis (AxSpA) and nonradiographic spondyloarthritis (nrSpA).

Insights into the role of HLA-B27 and cytokine-driven targeted therapies have transformed the lives of many patients with this male-dominated spondyloarthropathy; however, the genomic studies are yet to show more light on this.

This book authored by MA Khan and N Akkoc, 2nd Edition, has focused on AxSpA and covered all aspects including the impact of COVID-19 and SpA. It is very apt that Dr. Khan, himself a patient with SpA, has dedicated his time, knowledge, and experience to writing this crisp and informative book.

This book has very concise and in-depth analysis of both AxSpA and nrSpA, with special reference to global incidence and genome-wide association studies. HLA-B27 genomic studies have been focused in detail.

AxSpA and nrSpA may be used instead of ankylosis in view of its negative connotation.

Musculoskeletal and extra-articular manifestations have been described extensively with clear images.

OMERACT core domains for assessment and monitoring have been explained, and new terminologies symptom modifying antirheumatic drugs (SMARD) and disease controlling antirheumatic therapy (DC-ART) for the drug classifications are noteworthy.

Detailed chapters on clinical assessment, imaging, and laboratory evaluation would add to the knowledge base of the readers and indeed an additional tool for clinicians and researchers.

Evidence-based treatment guidelines and the 3Es initiative recommendations have been summarized beautifully.

The chapter on biologic therapy is superb, with insights into evidence-based recommendations, and the clarity on biosimilars and JAK inhibitors in SpA would guide the rheumatologists in developing countries such as India to decide on adequacy and plurality of treatment approaches. Newer drugs have also been mentioned with good study references.

The chapter on socioeconomic impact is laudable.

Chapters are easy to read and plenty of tables and figures.

+Overall, this book by MA Khan, the legendary writer, provides a comprehensive review and update on AxSpA which will help the rheumatologists and clinicians looking after the musculoskeletal health. I am sure the readers will enrich their clinical practice and implement this guidance to maintain long-term good health.






 

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