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REVIEW ARTICLE
Year : 2016  |  Volume : 11  |  Issue : 6  |  Page : 139-144

Neonatal lupus: An update


Department of Pediatrics, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Sathish Kumar
Department of Pediatrics, Christian Medical College, Vellore - 632 004, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-3698.194548

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Neonatal lupus erythematosus (NLE) is a syndrome that usually presents in the fetus or neonates that is caused by transplacental passage of autoantibodies from the mother. It is a clinical spectrum of cutaneous, cardiac, and systemic abnormalities observed in the newborn or infants whose mothers have autoantibodies against Ro/SSA and/or La/SSB. Congenital complete heart block is the most serious manifestation of NLE that can develop in utero or after birth. Multidisciplinary team involvement is indicated. This article will provide an overview the presentation of NLE and will review the evidence for current therapies.


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